DnaD

• Description: initiation of chromosome replication
  
  

Gene name	dnaD
Synonyms
Essential	yes PubMed
Product	initiation of chromosome replication
Function	DNA replication
MW, pI	27 kDa, 7.174
Gene length, protein length	696 bp, 232 aa
Immediate neighbours	nth, asnS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: DNA polymerase type-Y family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: DnaD-PriA, DnaD-DnaA, DnaD-DnaB PubMed, PubMed

• Localization: Membrane-proximal (Spotty) PubMed

Database entries

• Structure: 2C79 (N-terminal domain)

• Swiss prot entry: P39787

• KEGG entry: BSU22350

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135-2146. PubMed
2. Ishigo-Oka et al. (2001) DnaD protein of Bacillus subtilis interacts with DnaA, the initiator protein of replication. J. Bacteriol. 183: 2148-2150. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed