Difference between revisions of "RoxS"

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{{SubtiWiki regulon|[[ResD regulon]]}}
 
{{SubtiWiki regulon|[[ResD regulon]]}}
  
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= The [[RoxS regulon]] =
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* ''[[ppnKB]]'', ''[[sucC]]-[[sucD]]''
 
=The gene=
 
=The gene=
  
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* '''[[SubtInteract|Interactions]]:'''  
 
* '''[[SubtInteract|Interactions]]:'''  
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=The RNA=
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=== Basic information/ Evolution ===
 +
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* '''Catalyzed reaction/ biological activity:''' hybridizes to ''[[ppnKB]]'' and ''[[sucD]]'' mRNAs to inhibit their translation and to destabilize them {{PubMed|25643072}}
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=== Extended information on the RNA===
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* '''Kinetic information'''
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* '''[[SubtInteract|Interactions]]:'''
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** binds ''[[ppnKB]]'', and ''[[sucC]]-[[sucD]]'' mRNAs {{PubMed|25643072}}
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* '''[[Localization]]'''
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=== Database entries ===
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* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
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* '''Structure''':
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=== Additional information===
  
 
=Expression and regulation=
 
=Expression and regulation=
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* '''Additional information:'''
 
* '''Additional information:'''
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** the roxS RNA is degraded by the joined activities of [[rny|RNase Y]] (initial endonucleolytic cleavage) and RNase J1 (processive degradation) {{PubMed|25643072}}
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** the roxS-ppnKB and roxS-sucC RNA duplexes form a cleavage site for RNase III {{PubMed|25643072}}
  
 
=Biological materials =
 
=Biological materials =

Revision as of 12:32, 4 February 2015

  • Description: small RNA, controls expression of ppnKB and sucC-sucD

Gene name roxS
Synonyms rsaE
Essential no
Product trans-acting regulatory RNA
Function control of ppnKB and sucC-sucD expression
Gene length
Immediate neighbours yizD, yjbH
Gene sequence (+200bp)
Genetic context








Categories containing this gene/protein

ncRNA

This gene is a member of the following regulons

ResD regulon

The RoxS regulon

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • BsubCyc: no entry
  • DBTBS entry: no entry
  • SubtiList entry: no entry
  • Structure:

Additional information

  • Similar RNA:

The RNA

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: hybridizes to ppnKB and sucD mRNAs to inhibit their translation and to destabilize them PubMed

Extended information on the RNA

  • Kinetic information

Database entries

  • BsubCyc: ?
  • Structure:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • the roxS RNA is degraded by the joined activities of RNase Y (initial endonucleolytic cleavage) and RNase J1 (processive degradation) PubMed
    • the roxS-ppnKB and roxS-sucC RNA duplexes form a cleavage site for RNase III PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:


Labs working on this gene/RNA

Ciaran Condon, Paris

Your additional remarks

References