Difference between revisions of "YciC"

From SubtiWiki
Jump to: navigation, search
(Expression and regulation)
Line 114: Line 114:
  
 
* '''Operon:'''  
 
* '''Operon:'''  
** ''[[yciA]]-[[yciB]]-[[yciC]]'' {{PubMed|9811636}}  
+
** ''[[folE2]]-[[yciB]]-[[yciC]]'' {{PubMed|9811636}}  
 
** ''yciC'' {{PubMed|12426338}}
 
** ''yciC'' {{PubMed|12426338}}
  
Line 120: Line 120:
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
** ''[[yciA]]'':[[SigA]] {{PubMed|12426338}}
+
** ''[[folE2]]'':[[SigA]] {{PubMed|12426338}}
 
** ''[[yciC]]'':[[SigA]] {{PubMed|12426338}}
 
** ''[[yciC]]'':[[SigA]] {{PubMed|12426338}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** ''[[yciA]]'': induced by zinc starvation ([[Zur]]) {{PubMed|12426338}}
+
** ''[[folE2]]'': induced by zinc starvation ([[Zur]]) {{PubMed|12426338}}
 
** ''[[yciC]]'': induced by zinc starvation ([[Zur]]) {{PubMed|12426338}}
 
** ''[[yciC]]'': induced by zinc starvation ([[Zur]]) {{PubMed|12426338}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** ''[[yciA]]'': [[Zur]]: transcription repression in  the presence of zinc {{PubMed|12426338}}
+
** ''[[folE2]]'': [[Zur]]: transcription repression in  the presence of zinc {{PubMed|12426338}}
 
** ''[[yciC]]'': [[Zur]]: transcription repression in  the presence of zinc {{PubMed|12426338}}
 
** ''[[yciC]]'': [[Zur]]: transcription repression in  the presence of zinc {{PubMed|12426338}}
  

Revision as of 15:50, 6 February 2015

  • Description: putative metallochaperone

Gene name yciC
Synonyms
Essential no
Product putative metallochaperone
Function zinc uptake
Gene expression levels in SubtiExpress: yciC
Metabolic function and regulation of this protein in SubtiPathways:
yciC
MW, pI 45 kDa, 4.399
Gene length, protein length 1191 bp, 397 aa
Immediate neighbours yczL, yckA
Sequences Protein DNA DNA_with_flanks
Genetic context
YciC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YciC expression.png
























Categories containing this gene/protein

trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins, phosphoproteins

This gene is a member of the following regulons

Zur regulon

The gene

Basic information

  • Locus tag: BSU03360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cobW C-terminal domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-58 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
    • folE2: Zur: transcription repression in the presence of zinc PubMed
    • yciC: Zur: transcription repression in the presence of zinc PubMed
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 448 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References