LytA

• Description: secretion of major autolysin LytC
  
  

Gene name	lytA
Synonyms	lppX
Essential	no
Product	secretion of major autolysin LytC
Function	autolysis
Gene expression levels in SubtiExpress: lytA
Metabolic function and regulation of this protein in SubtiPathways: LytA
MW, pI	11 kDa, 4.061
Gene length, protein length	306 bp, 102 aa
Immediate neighbours	lytB, tagU
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

This gene is a member of the following regulons

SigD regulon, SlrR regulon, YvrHb regulon

The gene

Basic information

• Locus tag: BSU35640

Database entries

• BsubCyc: BSU35640

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU35640

• Structure:

• UniProt: Q02112

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytA-lytB-lytC PubMed

• Expression browser: lytA PubMed

• Sigma factor: SigA PubMed, SigD PubMed

• Regulation:

• Regulatory mechanism:
  • SlrR (in complex with SinR: transcription repression PubMed
  • YvrHb: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A789 ( lytA::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: