Difference between revisions of "NadB"

From SubtiWiki
Jump to: navigation, search
Line 15: Line 15:
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27870 nadB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27870 nadB]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=NadB NadB]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58 kDa, 6.445   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 58 kDa, 6.445   

Revision as of 11:48, 8 April 2014

  • Description: L-aspartate oxidase

Gene name nadB
Synonyms
Essential no
Product L-aspartate oxidase
Function NAD biosynthesis
Gene expression levels in SubtiExpress: nadB
Metabolic function and regulation of this protein in SubtiPathways:
NadB
MW, pI 58 kDa, 6.445
Gene length, protein length 1593 bp, 531 aa
Immediate neighbours nadC, nifS
Sequences Protein DNA DNA_with_flanks
Genetic context
NadB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NadB expression.png
























Categories containing this gene/protein

biosynthesis of cofactors, phosphoproteins

This gene is a member of the following regulons

NadR regulon

The gene

Basic information

  • Locus tag: BSU27870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-aspartate + O2 = iminosuccinate + H2O2 (according to Swiss-Prot)
  • Protein family: NadB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-104 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of nicotinic acid (NadR) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

Your additional remarks

References