BsrA

• Description: 6S RNA, important for timing of sporulation
  
  

Gene name	bsrA
Synonyms
Essential	no
Product	6S RNA
Function	antagonist of SigA
Interactions involving this RNA in SubtInteract: BsrA
Gene length	190 bp
Immediate neighbours	yrvM, aspS
Gene sequence (+200bp)
Genetic context

Categories containing this gene/protein

sigma factors and their control, ncRNA

The gene

Basic information

• Locus tag: BSU_misc_RNA_41

Phenotypes of a mutant

• reduced growth rate PubMed
• delayed outgrowth from stationary phase PubMed
• altered timing of onset of sporulation (earlier sporulation) PubMed

Database entries

• BsubCyc: BSU_misc_RNA_41

• DBTBS entry: no entry

• SubtiList entry: no entry

• Structure:

Additional information

• Similar RNA: bsrB

• Interactions: BsrA-SigA-RNA polymerase

Expression and regulation

• Operon: bsrA PubMed

• Sigma factor: SigA PubMed

• Regulation: expressed in vegetative cells PubMed

• Regulatory mechanism:

• Additional information: transcribed as 201 nt RNA, processed to mature 190 bp 6S RNA PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

Labs working on this gene/RNA

Kouji Nakamura, Tsukuba, University, Japan

Roland Hartmann, Philipps-Universität Marburg, Marburg, Germany, Homepage

References

Reviews

Amy T Cavanagh, Karen M Wassarman
6S RNA, a global regulator of transcription in Escherichia coli, Bacillus subtilis, and beyond.
Annu Rev Microbiol: 2014, 68;45-60
[PubMed:24742053] [WorldCat.org] [DOI] (I p)

Benedikt Steuten, Sabine Schneider, Rolf Wagner
6S RNA: recent answers--future questions.
Mol Microbiol: 2014, 91(4);641-8
[PubMed:24308327] [WorldCat.org] [DOI] (I p)