Difference between revisions of "YloB"

From SubtiWiki
Jump to: navigation, search
Line 15: Line 15:
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15650 yloB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15650 yloB]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=YloB YloB]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 97 kDa, 8.714   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 97 kDa, 8.714   

Revision as of 11:54, 8 April 2014

  • Description: similar to the E. coli MgtA magnesium transporter

Gene name yloB
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: yloB
Metabolic function and regulation of this protein in SubtiPathways:
YloB
MW, pI 97 kDa, 8.714
Gene length, protein length 2670 bp, 890 aa
Immediate neighbours yloA, yloC
Sequences Protein DNA DNA_with_flanks
Genetic context
YloB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YloB expression.png















Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15650

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • ATP + H2O + Ca2+(Cis) = ADP + phosphate + Ca2+(Trans) (according to Swiss-Prot)
    • there is no indication for an implication of YloB in Mg2+ uptake (based on mutant phenotypes, failure to complement mutants defective in Mg2+ uptake) PubMed
  • Protein family: Type IIA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Catherine A Wakeman, Jonathan R Goodson, Vineetha M Zacharia, Wade C Winkler
Assessment of the requirements for magnesium transporters in Bacillus subtilis.
J Bacteriol: 2014, 196(6);1206-14
[PubMed:24415722] [WorldCat.org] [DOI] (I p)