DgkB

• Description: diacylglycerol kinase
  
  

Gene name	dgkB
Synonyms	yerQ
Essential	yes PubMed
Product	diacylglycerol kinase
Function	biosynthesis of lipoteichoic acid
Gene expression levels in SubtiExpress: dgkB
MW, pI	33 kDa, 5.635
Gene length, protein length	909 bp, 303 aa
Immediate neighbours	yerP, rlmCD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes

The gene

Basic information

• Locus tag: BSU06720

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU06720

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): BmrU

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU06720

• Structure: 3S40 (from B. anthracis, 32% identity, 68% similarity)

• UniProt: O31502

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: dgkB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • GP1391 dgkB::cat ltaS::aphA3, available in Jörg Stülke's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Satoshi Matsuoka, Michihiro Hashimoto, Yusuke Kamiya, Takeshi Miyazawa, Kazuki Ishikawa, Hiroshi Hara, Kouji Matsumoto
The Bacillus subtilis essential gene dgkB is dispensable in mutants with defective lipoteichoic acid synthesis.
Genes Genet Syst: 2011, 86(6);365-76
[PubMed:22451476] [WorldCat.org] [DOI] (I p)

Agoston Jerga, Ying-Jie Lu, Gustavo E Schujman, Diego de Mendoza, Charles O Rock
Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis.
J Biol Chem: 2007, 282(30);21738-45
[PubMed:17535816] [WorldCat.org] [DOI] (P p)