YaaT

• Description: control of the phosphorelay, required for the achieving a sufficient level of Spo0A-P for sporulation initiation
  
  

Gene name	yaaT
Synonyms
Essential	no
Product	part of the YaaT-YmcA-YlbF complex
Function	regulation of sporulation initiation
Gene expression levels in SubtiExpress: yaaT
Interactions involving this protein in SubtInteract: YaaT
MW, pI	31 kDa, 4.838
Gene length, protein length	825 bp, 275 aa
Immediate neighbours	holB, yabA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphorelay, membrane proteins

The gene

Basic information

• Locus tag: BSU00320

Phenotypes of a mutant

• block of sporulation at stage 0 PubMed
• strongly reduced genetic competence, strongly reduced sporulation PubMed

Database entries

• BsubCyc: BSU00320

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YmcA-YlbF-YaaT, this complex stimulates Spo0A phosphorylation in the phosphorelay PubMed

• Localization:
  • peripheral membrane, as well as to the septum, during sporulation PubMed

Database entries

• BsubCyc: BSU00320

• Structure:

• UniProt: P37541

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yaaQ-yaaR-holB-yaaT-yabA-yabB-yazA-yabC PubMed

• Expression browser: yaaT PubMed

• Sigma factor:

• Regulation:
  • expressed during growth and the transition phase, expression is erduced in stationary phase PubMed

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 116 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 172 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: