Difference between revisions of "FtsA"

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(Phenotypes of a mutant)
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* '''Description:''' cell-division protein, membrane anchor for [[FtsZ]] <br/><br/>
+
* '''Description:''' [[cell division]] protein, membrane anchor for [[FtsZ]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || cell-division protein
+
|style="background:#ABCDEF;" align="center"| '''Product''' || [[cell division]] protein
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || formation of Z-ring
 
|style="background:#ABCDEF;" align="center"|'''Function''' || formation of Z-ring
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* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactors:'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 
** [[FtsZ]]-[[FtsA]] {{PubMed|16159787}}
 
** [[FtsZ]]-[[FtsA]] {{PubMed|16159787}}
 +
** [[PlsX]]-[[FtsA]] {{PubMed|24224907}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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<pubmed> 19680248 </pubmed>
 
<pubmed> 19680248 </pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed>16796675,12081956,16159787,11298280,18776011,9287012,1569582,10878122,7592498, 20566861 23036588 23701187 24218584</pubmed>
+
<pubmed>16796675,12081956,16159787,11298280,18776011,9287012,1569582,10878122,7592498, 20566861 23036588 23701187 24218584 24224907</pubmed>
 
+
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:22, 12 January 2014

Gene name ftsA
Synonyms spoIIN
Essential no
Product cell division protein
Function formation of Z-ring
Gene expression levels in SubtiExpress: ftsA
Interactions involving this protein in SubtInteract: FtsA
MW, pI 47 kDa, 5.094
Gene length, protein length 1320 bp, 440 aa
Immediate neighbours sbp, ftsZ
Sequences Protein DNA DNA_with_flanks
Genetic context
FtsA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FtsA expression.png















Categories containing this gene/protein

cell division, membrane proteins

This gene is a member of the following regulons

SigH regulon, WalR regulon

The gene

Basic information

  • Locus tag: BSU15280

Phenotypes of a mutant

  • cells become elongated PubMed
  • the ftsA mutation is synthetically lethal with a sepF mutation PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsA/mreB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications