Difference between revisions of "UvrC"
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28490&redirect=T BSU28490] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/uvrC.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/uvrC.html] | ||
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU28490&redirect=T BSU28490] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3C65 3C65] (5' endonuclease domain, Geobacillus stearothermophilus) | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=3C65 3C65] (5' endonuclease domain, Geobacillus stearothermophilus) |
Revision as of 14:26, 2 April 2014
- Description: excinuclease ABC (subunit C)
Gene name | uvrC |
Synonyms | uvrB |
Essential | no |
Product | excinuclease ABC (subunit C) |
Function | DNA repair after UV damage |
Gene expression levels in SubtiExpress: uvrC | |
Interactions involving this protein in SubtInteract: UvrC | |
MW, pI | 69 kDa, 9.503 |
Gene length, protein length | 1794 bp, 598 aa |
Immediate neighbours | lysC, trxA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28490
Phenotypes of a mutant
Database entries
- BsubCyc: BSU28490
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: uvrC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU28490
- Structure: 3C65 (5' endonuclease domain, Geobacillus stearothermophilus)
- UniProt: P14951
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: uvrC PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559]
[WorldCat.org]
[DOI]
(I p)
James J Truglio, Deborah L Croteau, Bennett Van Houten, Caroline Kisker
Prokaryotic nucleotide excision repair: the UvrABC system.
Chem Rev: 2006, 106(2);233-52
[PubMed:16464004]
[WorldCat.org]
[DOI]
(P p)
Bennett Van Houten, Deborah L Croteau, Matthew J DellaVecchia, Hong Wang, Caroline Kisker
'Close-fitting sleeves': DNA damage recognition by the UvrABC nuclease system.
Mutat Res: 2005, 577(1-2);92-117
[PubMed:15927210]
[WorldCat.org]
[DOI]
(P p)
A Sancar
Mechanisms of DNA excision repair.
Science: 1994, 266(5193);1954-6
[PubMed:7801120]
[WorldCat.org]
[DOI]
(P p)
Original publications