YqfL

• Description: Modulator of CcpN activity
  
  

Gene name	yqfL
Synonyms
Essential	no
Product	modulator of CcpN activity
Function	inhibits CcpN activity
Gene expression levels in SubtiExpress: yqfL
MW, pI	30,4 kDa, 5.78
Gene length, protein length	810 bp, 270 amino acids
Immediate neighbours	yqxD, ccpN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

carbon core metabolism, transcription factors and their control

The gene

Basic information

• Locus tag: BSU25240

Database entries

• BsubCyc: BSU25240

• DBTBS entry: [1]

• SubtiList entry:[2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: negative effector of CcpN activity PubMed

• Protein family: pyruvate, phosphate dikinase regulatory protein family (according to Swiss-Prot) pyruvate, phosphate dikinase regulatory protein family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: nucleotide binding domain (ATP) (151–158)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU25240

• Structure:

• UniProt: P54470

• KEGG entry: [3]

• E.C. number: 2.7.-.-

Expression and regulation

• Operon: ccpN-yqfL PubMed

• Expression browser: yqfL PubMed

• Sigma factor:

• Regulation: constitutive PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France

References

Pascale Servant, Dominique Le Coq, Stéphane Aymerich
CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes.
Mol Microbiol: 2005, 55(5);1435-51
[PubMed:15720552] [WorldCat.org] [DOI] (P p)