Difference between revisions of "AraE"
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33960 araE] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33960 araE] | ||
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− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=araE araE]''' |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.259 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 9.259 |
Revision as of 11:41, 7 January 2014
- Description: L-arabinose permease
Gene name | araE |
Synonyms | yvbR |
Essential | no |
Product | L-arabinose permease |
Function | uptake of arabinose, galactose and xylose |
Gene expression levels in SubtiExpress: araE | |
Metabolic function and regulation of this protein in SubtiPathways: araE | |
MW, pI | 50 kDa, 9.259 |
Gene length, protein length | 1392 bp, 464 aa |
Immediate neighbours | cggR, araR |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transporters/ other, utilization of specific carbon sources, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33960
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transports arabinose, and also xylose and galactose PubMed
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- UniProt: P96710
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: araE PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Esben M Quistgaard, Christian Löw, Per Moberg, Lionel Trésaugues, Pär Nordlund
Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat Struct Mol Biol: 2013, 20(6);766-8
[PubMed:23624861]
[WorldCat.org]
[DOI]
(I p)
José Manuel Inácio, Carla Costa, Isabel de Sá-Nogueira
Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 9);2345-2355
[PubMed:12949161]
[WorldCat.org]
[DOI]
(P p)
L J Mota, P Tavares, I Sá-Nogueira
Mode of action of AraR, the key regulator of L-arabinose metabolism in Bacillus subtilis.
Mol Microbiol: 1999, 33(3);476-89
[PubMed:10417639]
[WorldCat.org]
[DOI]
(P p)
O Krispin, R Allmansberger
The Bacillus subtilis AraE protein displays a broad substrate specificity for several different sugars.
J Bacteriol: 1998, 180(12);3250-2
[PubMed:9620981]
[WorldCat.org]
[DOI]
(P p)
I Sá-Nogueira, S S Ramos
Cloning, functional analysis, and transcriptional regulation of the Bacillus subtilis araE gene involved in L-arabinose utilization.
J Bacteriol: 1997, 179(24);7705-11
[PubMed:9401028]
[WorldCat.org]
[DOI]
(P p)