AtpH

• Description: ATP synthase, part of the F1 complex (subunit delta)
  
  

Gene name	atpH
Synonyms
Essential	no
Product	ATP synthase (subunit delta))
Function	ATP synthesis
Gene expression levels in SubtiExpress: atpH
Interactions involving this protein in SubtInteract: AtpH
MW, pI	19 kDa, 9.572
Gene length, protein length	543 bp, 181 aa
Immediate neighbours	atpA, atpF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ATP synthesis, phosphoproteins, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU36840

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP synthesis see a video

• Protein family: ATPase delta chain family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-159 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • A(1)-B(2)-C(12) - alpha(3)-beta(3)-gamma-delta-epsilon

• Localization:
  • membrane (Heterogeneous) PubMed
  • peripheral via theF0 complex

Database entries

• Structure: see here an overview on ATPase structure

• UniProt: P37811

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC PubMed

• Expression browser: atpH PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Alexander K W Elsholz, Kürsad Turgay, Stephan Michalik, Bernd Hessling, Katrin Gronau, Dan Oertel, Ulrike Mäder, Jörg Bernhardt, Dörte Becher, Michael Hecker, Ulf Gerth
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
Proc Natl Acad Sci U S A: 2012, 109(19);7451-6
[PubMed:22517742] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

M Santana, M S Ionescu, A Vertes, R Longin, F Kunst, A Danchin, P Glaser
Bacillus subtilis F0F1 ATPase: DNA sequence of the atp operon and characterization of atp mutants.
J Bacteriol: 1994, 176(22);6802-11
[PubMed:7961438] [WorldCat.org] [DOI] (P p)