Difference between revisions of "ECF transporter"
(→The substrate-specific S components of the ECF transporters) |
(→The substrate-specific S components of the ECF transporters) |
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* [[YhfU]]: uptake of biotin | * [[YhfU]]: uptake of biotin | ||
* [[TrpP]]: uptake of tryptophan | * [[TrpP]]: uptake of tryptophan | ||
| − | * [[YuiG]]: unknown specificity | + | * [[YuiG]]: unknown specificity, may also transport biotin |
== Important reviews and publications == | == Important reviews and publications == | ||
<pubmed>23584589 , 21135102, 20497229, </pubmed> | <pubmed>23584589 , 21135102, 20497229, </pubmed> | ||
Revision as of 19:17, 13 July 2013
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Contents
ECF transporters are required for the uptake of micronutrients such as cofactors (vitamins), metal ions, or amino acids. The transporters are composed of three general components (membrane spanning T protein und two ATP-hydrolyzing A proteins) and substrate-specific S proteins.
In B. subtilis, there are four known substrates for ECF transporters, riboflavin, thiamine, biotin, and tryptophan.
The general components of the ECF transporters
- ybxA ATP-binding A1 protein (EcfA1)
- ybaE ATP-binding A2 protein (EcfA2)
- ybaF membrane-spanning T protein (EcfT)
The substrate-specific S components of the ECF transporters
- RibU: uptake of riboflavin
- ThiT: uptake of thiamine
- YhfU: uptake of biotin
- TrpP: uptake of tryptophan
- YuiG: unknown specificity, may also transport biotin
Important reviews and publications
