Difference between revisions of "PsdR"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34720 psdR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34720 psdR]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PsdR PsdR]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=PsdR PsdR]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 4.676   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 4.676   

Revision as of 14:22, 18 November 2013

  • Description: two-component response regulator, induction of psdA-psdB in response to lipid II-binding lantibiotics, such as nisin and gallidermin

Gene name psdR
Synonyms yvcP
Essential no
Product two-component response regulator
Function resistance against toxic peptides
Gene expression levels in SubtiExpress: psdR
Interactions involving this protein in SubtInteract: PsdR
MW, pI 27 kDa, 4.676
Gene length, protein length 711 bp, 237 aa
Immediate neighbours psdS, yvzJ
Sequences Protein DNA DNA_with_flanks
Genetic context
YvcP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PsdR expression.png
























Categories containing this gene/protein

transcription factors and their control, resistance against toxins/ antibiotics, phosphoproteins

This gene is a member of the following regulons

The PsdR regulon: psdA-psdB

The gene

Basic information

  • Locus tag: BSU34720

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by PsdS on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed