LytT

• Description: two-component response regulator, regulation of the rate of autolysis
  
  

Gene name	lytT
Synonyms
Essential	no
Product	two-component response regulator
Function	regulation of the rate of autolysis
Gene expression levels in SubtiExpress: lytT
Interactions involving this protein in SubtInteract: LytT
MW, pI	27 kDa, 5.081
Gene length, protein length	723 bp, 241 aa
Immediate neighbours	ysbA, lytS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

cell wall degradation/ turnover, transcription factors and their control, membrane proteins, phosphoproteins

The gene

Basic information

• Locus tag: BSU28920

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on Asp by LytS

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • LytT-LytS

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94514

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytT PubMed

• Expression browser: lytT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)

A Wipat, N Carter, S C Brignell, B J Guy, K Piper, J Sanders, P T Emmerson, C R Harwood
The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism.
Microbiology (Reading): 1996, 142 ( Pt 11);3067-78
[PubMed:8969504] [WorldCat.org] [DOI] (P p)