Difference between revisions of "RecJ"
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|style="background:#ABCDEF;" align="center"| '''Product''' || single-strand DNA-specific exonuclease | |style="background:#ABCDEF;" align="center"| '''Product''' || single-strand DNA-specific exonuclease | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27620 yrvE] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27620 yrvE] | ||
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=References= | =References= | ||
− | + | == Reviews == | |
− | <pubmed>15241682 11948165 10498723</pubmed> | + | <pubmed> 22933559 </pubmed> |
+ | == Original publications == | ||
+ | <pubmed>15241682 11948165 10498723 21170359,21205011</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 15:55, 13 September 2013
- Description: single-strand DNA-specific exonuclease
Gene name | yrvE |
Synonyms | recJ |
Essential | no |
Product | single-strand DNA-specific exonuclease |
Function | DNA repair |
Gene expression levels in SubtiExpress: yrvE | |
Interactions involving this protein in SubtInteract: YrvE | |
Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation) | |
MW, pI | 87 kDa, 5.181 |
Gene length, protein length | 2358 bp, 786 aa |
Immediate neighbours | apt, yrvD |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
stringent response, Efp-dependent proteins
The gene
Basic information
- Locus tag: BSU27620
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: recJ family (according to Swiss-Prot)
- Paralogous protein(s): YorK
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32044
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
- translation is likely to require Efp due to the presence of several consecutive proline residues PubMed
Biological materials
- Mutant:
- GP895 (recJ::kan), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Justin S Lenhart, Jeremy W Schroeder, Brian W Walsh, Lyle A Simmons
DNA repair and genome maintenance in Bacillus subtilis.
Microbiol Mol Biol Rev: 2012, 76(3);530-64
[PubMed:22933559]
[WorldCat.org]
[DOI]
(I p)
Original publications