SpoVE

• Description: required for spore cortex peptidoglycan synthesis
  
  

Gene name	spoVE
Synonyms
Essential	no
Product	unknown
Function	spore cortex peptidoglycan synthesis
Gene expression levels in SubtiExpress: spoVE
Interactions involving this protein in SubtInteract: SpoVE
Metabolic function and regulation of this protein in SubtiPathways: Cell wall
MW, pI	39 kDa, 9.853
Gene length, protein length	1098 bp, 366 aa
Immediate neighbours	murD, murG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU15210

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)

• Paralogous protein(s): FtsW, RodA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SpoVD-SpoVE PubMed, this protects SpoVE from proteolytic degradation PubMed

• Localization: integral membrane protein, forespore PubMed

Database entries

• Structure:

• UniProt: P07373

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • murE-mraY-murD-spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • spoVE PubMed

• Expression browser: spoVE PubMed

• Sigma factor:
  • spoVE: SigE PubMed

• Regulation:
  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: