Difference between revisions of "AdeR"
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Revision as of 14:28, 16 May 2013
- Description: transcription activator (PucR family) for ald gene expression
| Gene name | adeR |
| Synonyms | yukF |
| Essential | no |
| Product | transcription activator (PucR family) |
| Function | control of ald expression |
| MW, pI | 50 kDa, 8.147 |
| Gene length, protein length | 1302 bp, 434 aa |
| Immediate neighbours | yukE, ald |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control, utilization of amino acids
This gene is a member of the following regulons
The AdeR regulon
The gene
Basic information
- Locus tag: BSU31920
Phenotypes of a mutant
- sporulation defect due to lack of ald expression PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of ald gene expression in the presence of alanine PubMed
- Protein family: PucR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on Ser-395 PubMed
- Cofactor(s):
- Effectors of protein activity: L-alanine PubMed
Database entries
- Structure:
- UniProt: P71073
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: adeR PubMed
- Sigma factor:
- Regulation:
- constitutively expressed PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Boumediene Soufi, Chanchal Kumar, Florian Gnad, Matthias Mann, Ivan Mijakovic, Boris Macek
Stable isotope labeling by amino acids in cell culture (SILAC) applied to quantitative proteomics of Bacillus subtilis.
J Proteome Res: 2010, 9(7);3638-46
[PubMed:20509597]
[WorldCat.org]
[DOI]
(I p)
K J Siranosian, K Ireton, A D Grossman
Alanine dehydrogenase (ald) is required for normal sporulation in Bacillus subtilis.
J Bacteriol: 1993, 175(21);6789-96
[PubMed:8226620]
[WorldCat.org]
[DOI]
(P p)
