Difference between revisions of "YqfL"

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Revision as of 13:57, 16 May 2013

  • Description: Modulator of CcpN activity

Gene name yqfL
Synonyms
Essential no
Product modulator of CcpN activity
Function inhibits CcpN activity
Gene expression levels in SubtiExpress: yqfL
MW, pI 30,4 kDa, 5.78
Gene length, protein length 810 bp, 270 amino acids
Immediate neighbours yqxD, ccpN
Sequences Protein DNA DNA_with_flanks
Genetic context
YqfL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqfL expression.png

























Categories containing this gene/protein

carbon core metabolism, transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry:[2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: negative effector of CcpN activity PubMed
  • Protein family: pyruvate, phosphate dikinase regulatory protein family (according to Swiss-Prot) pyruvate, phosphate dikinase regulatory protein family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: nucleotide binding domain (ATP) (151–158)
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France


Your additional remarks

References

Pascale Servant, Dominique Le Coq, Stéphane Aymerich
CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes.
Mol Microbiol: 2005, 55(5);1435-51
[PubMed:15720552] [WorldCat.org] [DOI] (P p)