Difference between revisions of "Upp"
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Revision as of 14:48, 16 May 2013
- Description: uracil phosphoribosyltransferase
| Gene name | upp |
| Synonyms | ipc-35d |
| Essential | no |
| Product | uracil phosphoribosyltransferase |
| Function | UMP synthesis |
| Gene expression levels in SubtiExpress: upp | |
| Metabolic function and regulation of this protein in SubtiPathways: Pyrimidines, Nucleotides (regulation) | |
| MW, pI | 22 kDa, 5.863 |
| Gene length, protein length | 627 bp, 209 aa |
| Immediate neighbours | atpI, glyA |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36890
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: UPRTase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2EHJ (from Escherichia coli, 52% identity, 73% similarity)
- UniProt: P39149
- KEGG entry: [3]
- E.C. number: 2.4.2.9
Additional information
Expression and regulation
- Operon: upp PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
J Martinussen, P Glaser, P S Andersen, H H Saxild
Two genes encoding uracil phosphoribosyltransferase are present in Bacillus subtilis.
J Bacteriol: 1995, 177(1);271-4
[PubMed:7798145]
[WorldCat.org]
[DOI]
(P p)
