Difference between revisions of "YlxS"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[polC]]'', ''[[nusA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[polC]]'', ''[[nusA]]''
 
|-
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16590 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16590 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16590 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16590 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16590 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16590 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ylxS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ylxS_context.gif]]

Revision as of 10:15, 14 May 2013

  • Description: similar to 30S ribosomal subunit maturation protein


Gene name ylxS
Synonyms ymxA
Essential no
Product unknown
Function ribosome maturation
Gene expression levels in SubtiExpress: ylxS
MW, pI 17 kDa, 4.482
Gene length, protein length 468 bp, 156 aa
Immediate neighbours polC, nusA
Sequences Protein DNA DNA_with_flanks
Genetic context
YlxS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YlxS expression.png
























Categories containing this gene/protein

translation

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU16590

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: UPF0090 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:
    • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Stefan Nord, Göran O Bylund, J Mattias Lövgren, P Mikael Wikström
The RimP protein is important for maturation of the 30S ribosomal subunit.
J Mol Biol: 2009, 386(3);742-53
[PubMed:19150615] [WorldCat.org] [DOI] (I p)

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)

K Shazand, J Tucker, M Grunberg-Manago, J C Rabinowitz, T Leighton
Similar organization of the nusA-infB operon in Bacillus subtilis and Escherichia coli.
J Bacteriol: 1993, 175(10);2880-7
[PubMed:8491709] [WorldCat.org] [DOI] (P p)