KtrD

• Description: low affinity potassium transporter KtrC-KtrD, integral membrane subunit
  
  

Gene name	ktrD
Synonyms	ykrM
Essential	no
Product	low affinity potassium transporter KtrC-KtrD, integral membrane subunit (proton symport)
Function	potassium uptake
Gene expression levels in SubtiExpress: ktrD
Interactions involving this protein in SubtInteract: KtrD
Metabolic function and regulation of this protein in SubtiPathways: Metal ion homeostasis, Stress
MW, pI	49 kDa, 9.224
Gene length, protein length	1347 bp, 449 aa
Immediate neighbours	htpX, ykzP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), coping with hyper-osmotic stress, membrane proteins

The gene

Basic information

• Locus tag: BSU13500

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s): KtrB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • KtrC-KtrD PubMed

• Localization: integral membrane protein PubMed

Database entries

• Structure:

• UniProt: O31658

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ktrD PubMed

• Expression browser: ktrD PubMed

• Sigma factor:

• Regulation: constitutively expressed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A956 ( ktrD::tet), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, University of Marburg, Germany homepage

References

Gudrun Holtmann, Evert P Bakker, Nobuyuki Uozumi, Erhard Bremer
KtrAB and KtrCD: two K+ uptake systems in Bacillus subtilis and their role in adaptation to hypertonicity.
J Bacteriol: 2003, 185(4);1289-98
[PubMed:12562800] [WorldCat.org] [DOI] (P p)