Difference between revisions of "CheC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU16450 cheC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16450 cheC]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/CheC CheC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/CheC CheC]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cheW]]'', ''[[cheD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cheW]]'', ''[[cheD]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13518&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16450 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16450 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16450 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:cheC_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:cheC_context.gif]]

Revision as of 12:51, 13 May 2013

  • Description: control of chemotaxis by interacting with CheD, CheY-P phosphatase, inhibition of CheR-mediated methylation of MCPs

Gene name cheC
Synonyms ylxJ
Essential no
Product CheY-P phosphatase
Function motility and chemotaxis
Gene expression levels in SubtiExpress: cheC
Interactions involving this protein in SubtInteract: CheC
MW, pI 22 kDa, 4.035
Gene length, protein length 627 bp, 209 aa
Immediate neighbours cheW, cheD
Sequences Protein DNA Advanced_DNA
Genetic context
CheC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CheC expression.png















Categories containing this gene/protein

protein modification, motility and chemotaxis

This gene is a member of the following regulons

CodY regulon, SigD regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU16450

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • CheY-P phosphatase
    • controls binding of CheD to chemoreceptors in response to the levels of CheY-P PubMed
  • Protein family: cheC family (according to Swiss-Prot)
  • Paralogous protein(s):FliY

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: interaction with CheD enhances phosphatase activity towards CheY-P PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium, CheC is present with 770 +/- 330 molecules per cell PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References