Difference between revisions of "YngI"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism, leucine utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || mother cell metabolism, leucine utilization | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18250 yngI] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 5.978 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 61 kDa, 5.978 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yngH]]'', ''[[yngJ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yngH]]'', ''[[yngJ]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18250 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18250 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18250 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yngI_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yngI_context.gif]] | ||
Revision as of 12:57, 13 May 2013
- Description: aceto-acetyl-CoA ligase, may be involved in surfactin production
| Gene name | yngI |
| Synonyms | |
| Essential | no |
| Product | aceto-acetyl-CoA ligase |
| Function | mother cell metabolism, leucine utilization |
| Gene expression levels in SubtiExpress: yngI | |
| MW, pI | 61 kDa, 5.978 |
| Gene length, protein length | 1647 bp, 549 aa |
| Immediate neighbours | yngH, yngJ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
utilization of amino acids, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + acetoacetate + CoA <=> AMP + diphosphate + acetoacetyl-CoA PubMed
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31826
- KEGG entry: [3]
- E.C. number: 6.2.1.16
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in Mohamed Marahiel's lab PubMed
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Femke I Kraas, Verena Helmetag, Melanie Wittmann, Matthias Strieker, Mohamed A Marahiel
Functional dissection of surfactin synthetase initiation module reveals insights into the mechanism of lipoinitiation.
Chem Biol: 2010, 17(8);872-80
[PubMed:20797616]
[WorldCat.org]
[DOI]
(I p)
Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Shane T Jensen, Erin M Conlon, Christiaan van Ooij, Jessica Silvaggi, José Eduardo González-Pastor, Masaya Fujita, Sigal Ben-Yehuda, Patrick Stragier, Jun S Liu, Richard Losick
The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis.
J Mol Biol: 2003, 327(5);945-72
[PubMed:12662922]
[WorldCat.org]
[DOI]
(P p)
