Difference between revisions of "Tgl"

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|style="background:#ABCDEF;" align="center"|'''Function''' || introduction of crosslinks in the spore coat protein [[GerQ]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || introduction of crosslinks in the spore coat protein [[GerQ]]
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU31270 tgl]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31270 tgl]
 
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|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 6.687   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 6.687   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mcpB]]'', ''[[yuzH]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mcpB]]'', ''[[yuzH]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15105&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31270 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31270 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31270 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:tgl_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:tgl_context.gif]]

Revision as of 13:42, 13 May 2013

  • Description: spore associated transglutaminase

Gene name tgl
Synonyms yuxF, yugV
Essential no
Product spore associated transglutaminase
Function introduction of crosslinks in the spore coat protein GerQ
Gene expression levels in SubtiExpress: tgl
MW, pI 28 kDa, 6.687
Gene length, protein length 735 bp, 245 aa
Immediate neighbours mcpB, yuzH
Sequences Protein DNA Advanced_DNA
Genetic context
Tgl context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Tgl expression.png
























Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU31270

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3 (according to Swiss-Prot), temperature-dependent modification of the coat proteins such as GerQ (together with YabG) PubMed
  • Protein family: bacillus TGase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage

Your additional remarks

References

Reviews

Ritsuko Kuwana
[Protein modification system in dormant cells].
Yakugaku Zasshi: 2009, 129(10);1221-5
[PubMed:19797877] [WorldCat.org] [DOI] (P p)

Original Publications