Difference between revisions of "TsaD"

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(Publications on the corresponding protein from other species)
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|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU05940 tsaD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU05940 tsaD]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/TsaD TsaD]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/TsaD TsaD]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydiD]]'', ''[[ydiF]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydiD]]'', ''[[ydiF]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12413&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU05940 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU05940 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU05940 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:gcp_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:gcp_context.gif]]

Revision as of 12:15, 13 May 2013

  • Description: required for threonyl carbamoyl adenosine (t6A) modification of tRNAs that pair with ANN codons in mRNA (together with TsaC), universally conserved protein

Gene name tsaD
Synonyms ydiE, gcp
Essential yes PubMed
Product tRNA modification enzyme
Function tRNA modification
Gene expression levels in SubtiExpress: tsaD
Interactions involving this protein in SubtInteract: TsaD
MW, pI 36 kDa, 5.016
Gene length, protein length 1038 bp, 346 aa
Immediate neighbours ydiD, ydiF
Sequences Protein DNA Advanced_DNA
Genetic context
Gcp context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Gcp expression.png















Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05940

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs using L-threonylcarbamoyl-AMP (TsaB-TsaD-TsaE) PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

universally conserved protein

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Publications on the corresponding protein from other species