Difference between revisions of "Rex"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of fermentation and anaerobic respiration | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of fermentation and anaerobic respiration | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU05970 rex] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydiG]]'', ''[[tatAY]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydiG]]'', ''[[tatAY]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU05970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU05970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU05970 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:ydiH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ydiH_context.gif]] | ||
Revision as of 12:15, 13 May 2013
- Description: transcriptional repressor of anaerobically expressed genes involved in anaerobic respiration and fermentation
| Gene name | rex |
| Synonyms | ydiH |
| Essential | no |
| Product | transcriptional repressor |
| Function | regulation of fermentation and anaerobic respiration |
| Gene expression levels in SubtiExpress: rex | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 23 kDa, 6.772 |
| Gene length, protein length | 645 bp, 215 aa |
| Immediate neighbours | ydiG, tatAY |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
regulators of electron transport, carbon core metabolism, transcription factors and their control
This gene is a member of the following regulons
The Rex regulon
The gene
Basic information
- Locus tag: BSU05970
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: transcriptional regulatory rex family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: NADH (indication of low oxygen concentration) releases Rex from DNA PubMed, Rex has a very highh affinity for NADH
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: O05521
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
- The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed
Biological materials
- Mutant: LUW292 (erm), GP834 (erm), both available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Claes von Wachenfeldt, Lund University, Sweden Homepage
Your additional remarks
References
Reviews
Elisabeth Härtig, Dieter Jahn
Regulation of the anaerobic metabolism in Bacillus subtilis.
Adv Microb Physiol: 2012, 61;195-216
[PubMed:23046954]
[WorldCat.org]
[DOI]
(I p)
Original publications
