Difference between revisions of "SrtN"
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* '''Mutant:''' | * '''Mutant:''' | ||
| − | ** GP1210 (''[[srtN]]''::''cat''), available in [[Stülke]] lab | + | ** GP1210 (''[[srtN]]''::''cat''), available in [[Jörg Stülke]]'s lab |
| − | + | ** 1A888 ( ''srtN''::''spec''), {{PubMed|19136592}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A888&Search=1A888 BGSC] | |
* '''Expression vector:''' | * '''Expression vector:''' | ||
Revision as of 12:15, 1 October 2012
- Description: protein deacetylase for the control of AcsA activity
| Gene name | srtN |
| Synonyms | yhdZ |
| Essential | no |
| Product | NAD(+)-dependent AcsA deacetylase |
| Function | control of AcsA activity |
| Gene expression levels in SubtiExpress: srtN | |
| MW, pI | 27 kDa, 5.134 |
| Gene length, protein length | 741 bp, 247 aa |
| Immediate neighbours | yhdY, yheN |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09650
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NAD+ + an acetylprotein = nicotinamide + O-acetyl-ADP-ribose + a protein (according to Swiss-Prot) deacetylates (and thereby activates) AcsA (together with AcuC) PubMed
- Protein family: deacetylase sirtuin-type domain (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O07595
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- GP1210 (srtN::cat), available in Jörg Stülke's lab
- 1A888 ( srtN::spec), PubMed, available at BGSC
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
