Difference between revisions of "SftA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || resolution of chromosome dimers | |style="background:#ABCDEF;" align="center"|'''Function''' || resolution of chromosome dimers | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29805 sftA] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 107 kDa, 5.052 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 107 kDa, 5.052 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29805 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29805 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29805 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]] | ||
Revision as of 13:37, 13 May 2013
- Description: DNA translocase
| Gene name | sftA |
| Synonyms | ytpS, cdtA |
| Essential | no |
| Product | DNA translocase |
| Function | resolution of chromosome dimers |
| Gene expression levels in SubtiExpress: sftA | |
| MW, pI | 107 kDa, 5.052 |
| Gene length, protein length | 2856 bp, 952 aa |
| Immediate neighbours | murC, ytpR |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29805
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
- the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
- Protein family:
- Paralogous protein(s): SpoIIIE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- forms a hexamer PubMed
Database entries
- Structure:
- UniProt: C0SP86
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Christine Kaimer, Peter L Graumann
Players between the worlds: multifunctional DNA translocases.
Curr Opin Microbiol: 2011, 14(6);719-25
[PubMed:22047950]
[WorldCat.org]
[DOI]
(I p)
Original publications
