PepF

• Description: oligoendopeptidase, inhibits sporulation upon overexpression
  
  

Gene name	pepF
Synonyms	yjbG
Essential	no
Product	oligoendopeptidase
Function	protein degradation
Gene expression levels in SubtiExpress: pepF
MW, pI	69 kDa, 5.131
Gene length, protein length	1827 bp, 609 aa
Immediate neighbours	coiA, yizD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphorelay

The gene

Basic information

• Locus tag: BSU11540

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M3B family (according to Swiss-Prot)

• Paralogous protein(s): YusX

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31605

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: pepF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A823 ( pepF::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Kyoko Kanamaru, Sophie Stephenson, Marta Perego
Overexpression of the PepF oligopeptidase inhibits sporulation initiation in Bacillus subtilis.
J Bacteriol: 2002, 184(1);43-50
[PubMed:11741842] [WorldCat.org] [DOI] (P p)