Difference between revisions of "RapA"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rapA_1315869_1317005_1 rapA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=rapA_1315869_1317005_1 rapA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|1378051}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1378051}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | ** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] | ||
** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** repressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
| − | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed] | + | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed] |
** expressed at high cell density ([[ComA]]) {{PubMed|16091051}} | ** expressed at high cell density ([[ComA]]) {{PubMed|16091051}} | ||
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** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ** [[CcpA]]: transcription repression [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed] | ||
** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ** [[Spo0A]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647 PubMed] | ||
| − | ** [[CodY]]: transcription repression | + | ** [[CodY]]: transcription repression {{PubMed|23569278,12618455}} |
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | + | <pubmed>8643670,8730857,11923303,22267516,14651647,12618455, 12107147, 19380751, 12850135 1378051 16091051 23569278</pubmed> | |
| − | <pubmed>8643670,8730857,11923303,,14651647,12618455, 12107147, 19380751, 12850135 1378051 16091051</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:32, 19 April 2013
- Description: response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay
| Gene name | rapA |
| Synonyms | gsiAA, spo0L |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of sporulation initiation |
| Gene expression levels in SubtiExpress: rapA | |
| Interactions involving this protein in SubtInteract: RapA | |
| Function and regulation of this protein in SubtiPathways: Phosphorelay | |
| MW, pI | 44 kDa, 4.848 |
| Gene length, protein length | 1134 bp, 378 aa |
| Immediate neighbours | yjoB, phrA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
protein modification, transcription factors and their control, phosphorelay, quorum sensing
This gene is a member of the following regulons
CodY regulon, ComA regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU12430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- modular organization comprising an amino terminal alpha-helical domain connected to a domain formed by six tetratricopeptide (TPR) repeats PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q00828
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
