Difference between revisions of "GabT"

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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of gamma-amino butyric acid and synthesis of norspermidine
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of gamma-amino butyric acid and synthesis of norspermidine
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03900 gabT]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03900 gabT]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 5.304   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 5.304   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gabR]]'', ''[[gabD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gabR]]'', ''[[gabD]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12198&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03900 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03900 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03900 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:gabT_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:gabT_context.gif]]

Revision as of 12:09, 13 May 2013

  • Description: gamma-aminobutyrate transaminase, general stress protein

Gene name gabT
Synonyms ycnG
Essential no
Product gamma-aminobutyrate transaminase
Function utilization of gamma-amino butyric acid and synthesis of norspermidine
Gene expression levels in SubtiExpress: gabT
MW, pI 47 kDa, 5.304
Gene length, protein length 1308 bp, 436 aa
Immediate neighbours gabR, gabD
Sequences Protein DNA Advanced_DNA
Genetic context
GabT context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GabT expression.png
























Categories containing this gene/protein

utilization of amino acids, miscellaneous metabolic pathways, biofilm formation

This gene is a member of the following regulons

GabR regulon

The gene

Basic information

  • Locus tag: BSU03900

Phenotypes of a mutant

    • block in norspermidine production PubMed
    • impaired biofilm disassembly PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate (according to Swiss-Prot)
  • Protein family: class-III pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed in the presence of gamma-butyric acid (GabR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References