Difference between revisions of "FadE"
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** ''[[fadN]]'': induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}} | ** ''[[fadN]]'': induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}} | ||
** ''[[fadN]]'': subject to carbon catabolite repression ([[CcpA]]-[[PtsH|HPr(Ser-P)]] {{PubMed|21398533}} | ** ''[[fadN]]'': subject to carbon catabolite repression ([[CcpA]]-[[PtsH|HPr(Ser-P)]] {{PubMed|21398533}} | ||
+ | ** strongly induced in response to glucose starvation in M9 medium {{PubMed|23033921}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' |
Revision as of 19:09, 8 October 2012
- Description: acyl-CoA dehydrogenase
Gene name | fadE |
Synonyms | yusJ |
Essential | no |
Product | acyl-CoA dehydrogenase |
Function | fatty acid degradation |
Gene expression levels in SubtiExpress: fadE | |
Metabolic function and regulation of this protein in SubtiPathways: Fatty acid degradation | |
MW, pI | 65 kDa, 5.146 |
Gene length, protein length | 1782 bp, 594 aa |
Immediate neighbours | yusI, fadA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed 500px |
Contents
Categories containing this gene/protein
utilization of lipids, membrane proteins
This gene is a member of the following regulons
CcpA regulon, FadR regulon, SdpR regulon
The gene
Basic information
- Locus tag: BSU32820
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)
- Protein family: acyl-CoA dehydrogenase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane PubMed
Database entries
- Structure: 2Z1Q (from Thermus thermophilus hb8, 52% identity, 68% similarity)
- UniProt: O32176
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed