Difference between revisions of "HisJ"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of histidine | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of histidine | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29620 hisJ] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ezrA]]'', ''[[refZ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ezrA]]'', ''[[refZ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29620 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29620 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29620 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:hisJ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:hisJ_context.gif]] | ||
Revision as of 13:36, 13 May 2013
- Description: histidinol phosphate phosphatase
| Gene name | hisJ |
| Synonyms | ytvP |
| Essential | no |
| Product | histidinol phosphate phosphatase |
| Function | biosynthesis of histidine |
| Gene expression levels in SubtiExpress: hisJ | |
| Metabolic function and regulation of this protein in SubtiPathways: His | |
| MW, pI | 30 kDa, 5.061 |
| Gene length, protein length | 804 bp, 268 aa |
| Immediate neighbours | ezrA, refZ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29620
Phenotypes of a mutant
auxotroph for histidine
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-histidinol phosphate + H2O = L-histidinol + phosphate (according to Swiss-Prot)
- Protein family: HisK subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34411
- KEGG entry: [2]
- E.C. number: 3.1.3.15
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Your additional remarks
References
D le Coq, S Fillinger, S Aymerich
Histidinol phosphate phosphatase, catalyzing the penultimate step of the histidine biosynthesis pathway, is encoded by ytvP (hisJ) in Bacillus subtilis.
J Bacteriol: 1999, 181(10);3277-80
[PubMed:10322033]
[WorldCat.org]
[DOI]
(P p)
