Difference between revisions of "PbpX"
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|style="background:#ABCDEF;" align="center"|'''Function''' || endopeptidase | |style="background:#ABCDEF;" align="center"|'''Function''' || endopeptidase | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16950 pbpX] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 9.711 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 9.711 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[recA]]'', ''[[rny]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[recA]]'', ''[[rny]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16950 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16950 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16950 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:pbpX_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:pbpX_context.gif]] | ||
Revision as of 12:53, 13 May 2013
- Description: penicillin-binding protein X
| Gene name | pbpX |
| Synonyms | |
| Essential | no |
| Product | penicillin-binding protein X |
| Function | endopeptidase |
| Gene expression levels in SubtiExpress: pbpX | |
| MW, pI | 43 kDa, 9.711 |
| Gene length, protein length | 1173 bp, 391 aa |
| Immediate neighbours | recA, rny |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16950
Phenotypes of a mutant
- increased sensitivity to lysozyme PubMed
- inactivation of pbpX strongly restores beta-lactam resistance in a sigM mutant PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
- localizes during sporulation to both asymmetric septa and the prespore Link to a summary
Database entries
- Structure:
- UniProt: O31773
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: pbpX PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
Warawan Eiamphungporn, John D Helmann
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Mol Microbiol: 2008, 67(4);830-48
[PubMed:18179421]
[WorldCat.org]
[DOI]
(P p)
Min Cao, John D Helmann
The Bacillus subtilis extracytoplasmic-function sigmaX factor regulates modification of the cell envelope and resistance to cationic antimicrobial peptides.
J Bacteriol: 2004, 186(4);1136-46
[PubMed:14762009]
[WorldCat.org]
[DOI]
(P p)
