Difference between revisions of "MtnD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || methionine salvage
 
|style="background:#ABCDEF;" align="center"|'''Function''' || methionine salvage
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13620 mtnD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU13620 mtnD]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cys_meth_and_sulfate_assimilation.html Cys, Met & Sulfate assimilation]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cys_meth_and_sulfate_assimilation.html Cys, Met & Sulfate assimilation]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mtnB]]'', ''[[ykvA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[mtnB]]'', ''[[ykvA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13235&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU13620 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU13620 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU13620 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ykrZ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ykrZ_context.gif]]

Revision as of 12:40, 13 May 2013

  • Description: 1,2,-dihydroxy-3-keto-5-methylthiopentene dioxygenase

Gene name mtnD
Synonyms ykrZ
Essential no
Product 1,2,-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Function methionine salvage
Gene expression levels in SubtiExpress: mtnD
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 20 kDa, 4.408
Gene length, protein length 534 bp, 178 aa
Immediate neighbours mtnB, ykvA
Sequences Protein DNA Advanced_DNA
Genetic context
YkrZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MtnD expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

S-box

The gene

Basic information

  • Locus tag: BSU13620

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 = 3-(methylthio)propanoate + formate + CO (according to Swiss-Prot)
  • Protein family: acireductone dioxygenase (ARD) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References