SpoIIID

• Description: transcriptional regulator (repressor or activator) of a subset of sigma-E-dependent genes
  
  

Gene name	spoIIID
Synonyms
Essential	no
Product	transcriptional regulator
Function	regulation of mother cell gene expression
Gene expression levels in SubtiExpress: spoIIID
Metabolic function and regulation of this protein in SubtiPathways: Asp, Asn, Cell wall
MW, pI	10 kDa, 9.496
Gene length, protein length	279 bp, 93 aa
Immediate neighbours	mbl, usd
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU36420

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds its DNA targets as a monomeric protein (possible due to the two DNA-binding motifs) PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two DNA-binding regions: HTH at the N-terminus and a basic region near the C-terminus PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2L0K (complex with DNA)

• UniProt: P15281

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: usd-spoIIID-mbl-flhO-flhP PubMed

• Expression browser: spoIIID PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed
• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed