HelD

• Description: DNA 3'-5' helicase IV
  
  

Gene name	helD
Synonyms	yvgS
Essential	no
Product	DNA 3'-5' helicase IV
Function	DNA repair and recombination
Gene expression levels in SubtiExpress: helD
MW, pI	89 kDa, 6.083
Gene length, protein length	2322 bp, 774 aa
Immediate neighbours	cysI, yvgT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination

The gene

Basic information

• Locus tag: BSU33450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UvrD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • HelD interacts with the RNA polymerase PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32215

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: helD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

B Carrasco, S Fernández, M A Petit, J C Alonso
Genetic recombination in Bacillus subtilis 168: effect of DeltahelD on DNA repair and homologous recombination.
J Bacteriol: 2001, 183(19);5772-7
[PubMed:11544244] [WorldCat.org] [DOI] (P p)