Difference between revisions of "RelA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis and degradation of (p)ppGpp, <br/>triggering the stringent response | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis and degradation of (p)ppGpp, <br/>triggering the stringent response | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27600 relA] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/pathways/murein/index.html Murein recycling]''' | ||
Revision as of 14:23, 7 August 2012
- Description: GTP pyrophosphokinase (stringent response)
| Gene name | relA |
| Synonyms | |
| Essential | no |
| Product | GTP pyrophosphokinase |
| Function | synthesis and degradation of (p)ppGpp, triggering the stringent response |
| Gene expression levels in SubtiExpress: relA | |
| Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation), Murein recycling | |
| MW, pI | 84 kDa, 6.964 |
| Gene length, protein length | 2202 bp, 734 aa |
| Immediate neighbours | yrvI, apt |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
metabolism of signalling nucleotides
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27600
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate (according to Swiss-Prot)
- Protein family: relA/spoT family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O54408
- KEGG entry: [3]
- E.C. number: 2.7.6.5
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
