Difference between revisions of "PbpA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || formation of a rod-shaped peptidoglycan cell wall, spore outgrowth | |style="background:#ABCDEF;" align="center"|'''Function''' || formation of a rod-shaped peptidoglycan cell wall, spore outgrowth | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25000 pbpA] | ||
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PbpA PbpA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PbpA PbpA] | ||
Revision as of 13:51, 7 August 2012
- Description: penicillin-binding protein PBP 2A
| Gene name | pbpA |
| Synonyms | yqgF |
| Essential | no |
| Product | penicillin-binding protein PBP 2A |
| Function | formation of a rod-shaped peptidoglycan cell wall, spore outgrowth |
| Gene expression levels in SubtiExpress: pbpA | |
| Interactions involving this protein in SubtInteract: PbpA | |
| MW, pI | 79 kDa, 9.571 |
| Gene length, protein length | 2148 bp, 716 aa |
| Immediate neighbours | pstS, yqgE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25000
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- part of the cell wall biosynthetic complex PubMed
- folding requires PrsA PubMed
- Localization: extracellular (signal peptide) PubMed
Database entries
- Structure:
- UniProt: P54488
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jeff Errington lab
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle University, UK homepage
Your additional remarks
References
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. Mol Microbiol. 2011 81(6): 1459-1473. PubMed:21815947
