NrnB

• Description: oligoribonuclease (nano-RNase)
  
  

Gene name	nrnB
Synonyms	yngD
Essential	no
Product	nano-RNase B
Function	degradation of RNA oligonucleotides
Gene expression levels in SubtiExpress: nrnB
MW, pI	46 kDa, 5.026
Gene length, protein length	1197 bp, 399 aa
Immediate neighbours	yngC, yngE
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

Rnases

The gene

Basic information

• Locus tag: BSU18200

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: degradation of RNA oligonucleotides PubMed

• Protein family: DHH/DHHA1 protein family of phosphoesterases PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31824

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: nrnB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ming Fang, Wencke-Maria Zeisberg, Ciaran Condon, Vasily Ogryzko, Antoine Danchin, Undine Mechold
Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis.
Nucleic Acids Res: 2009, 37(15);5114-25
[PubMed:19553197] [WorldCat.org] [DOI] (I p)