Difference between revisions of "NtdB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic neotrehalosadiamine | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic neotrehalosadiamine | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10540 ntdB] | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.352 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.352 | ||
Revision as of 16:32, 6 August 2012
| Gene name | ntdB |
| Synonyms | yhjK |
| Essential | no |
| Product | unknown |
| Function | synthesis of the antibiotic neotrehalosadiamine |
| Gene expression levels in SubtiExpress: ntdB | |
| MW, pI | 33 kDa, 5.352 |
| Gene length, protein length | 858 bp, 286 aa |
| Immediate neighbours | ntdC, ntdA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: Cof family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3GYG
- UniProt: O07565
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256]
[WorldCat.org]
[DOI]
(I p)
Original publications
Takashi Inaoka, Takenori Satomura, Yasutaro Fujita, Kozo Ochi
Novel gene regulation mediated by overproduction of secondary metabolite neotrehalosadiamine in Bacillus subtilis.
FEMS Microbiol Lett: 2009, 291(2);151-6
[PubMed:19087206]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753]
[WorldCat.org]
[DOI]
(P p)
Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444]
[WorldCat.org]
[DOI]
(P p)
