Difference between revisions of "NagZ"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[murQ]]-[[murR]]-[[murP]]-[[amiE]]-[[nagZ]]-[[ybbC]]'' {{PubMed|22383849}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbD_186452_188380_-1 nagZ] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbD_186452_188380_-1 nagZ] {{PubMed|22383849}} | ||
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=References= | =References= | ||
'''Additional references:''' {{PubMed|20826810}} | '''Additional references:''' {{PubMed|20826810}} | ||
| − | <pubmed>10627040, 20400549 4628806 4196675</pubmed> | + | <pubmed>10627040, 20400549 4628806 4196675 22383849</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:20, 19 April 2012
- Description: N-acetylglucosaminidase
| Gene name | nagZ |
| Synonyms | yzbA, ybbD |
| Essential | no |
| Product | N-acetylglucosaminidase |
| Function | cell wall recycling |
| Metabolic function and regulation of this protein in SubtiPathways: Murein recycling | |
| MW, pI | 70 kDa, 9.76 |
| Gene length, protein length | 1926 bp, 642 aa |
| Immediate neighbours | ybbC, amiE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU01660
Phenotypes of a mutant
increased autolysis PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: cleaves muropeptides derived from peptidoglycan, but not peptidoglycan itself PubMed
- Protein family: glycosyl hydrolase 3 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (with signal peptide), remains to some extent cell wall-associated PubMed
Database entries
- UniProt: P40406
- KEGG entry: [2]
- E.C. number:
Additional information
The gene is mis-annotated in KEGG as an ortholog of beta-N-acetylhexosaminidase EC 3.2.1.52. It is marked in MetaCyc as “similar to beta-hexosaminidase”. No EC annotation is available in Swiss-ProtSwiss-Prot.supporting the annotation is available. PubMed
Expression and regulation
- Sigma factor:
- Regulation:
- expressed in late exponential and early stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: available in Christoph Mayer's lab PubMed
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional references: PubMed
