Difference between revisions of "PckA"
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* '''Regulation:''' repressed (35-times) Glc, repressor [[CcpN]] [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+15720552 PubMed] | * '''Regulation:''' repressed (35-times) Glc, repressor [[CcpN]] [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+15720552 PubMed] | ||
| − | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' transcription repression |
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 18:07, 13 January 2009
- Description: phosphoenolpyruvate carboxykinase synthesises phosphoenolpyrovat out of oxalacetate
| Gene name | pckA |
| Synonyms | ppc |
| Essential | no |
| Product | phosphoenolpyruvate carboxykinase |
| Function | synthesis of phosphoenolpyrovat |
| MW, pI | 58,1 kDa, 5.12 |
| Gene length, protein length | 1581 bp, 527 amino acids |
| Immediate neighbours | metK, ytmB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
The gene
Basic information
- Coordinates: 3128579 - 3130159
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + oxaloacetate = ADP + phosphoenolpyruvate + CO(2)
- Protein family: phosphoenolpyruvate carboxykinase [ATP] family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Nucleotide binding Domain (233–240)
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism: transcription repression
- Additional information:
Biological materials
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
