Difference between revisions of "Kbl"
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| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=kbl_1771517_1772695_1 kbl] {{PubMed|22383849}} |
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=Biological materials = | =Biological materials = | ||
Revision as of 09:25, 13 April 2012
- Description: 2-amino-3-ketobutyrate CoA ligase
| Gene name | kbl |
| Synonyms | |
| Essential | no |
| Product | 2-amino-3-ketobutyrate CoA ligase |
| Function | threonine utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 43 kDa, 6.25 |
| Gene length, protein length | 1176 bp, 392 aa |
| Immediate neighbours | tdh, ymcB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17000
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acetyl-CoA + glycine = CoA + 2-amino-3-oxobutanoate (according to Swiss-Prot)
- Protein family: class-II pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: O31777
- KEGG entry: [2]
- E.C. number: 2.3.1.29
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
A Schmidt, J Sivaraman, Y Li, R Larocque, J A Barbosa, C Smith, A Matte, J D Schrag, M Cygler
Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism.
Biochemistry: 2001, 40(17);5151-60
[PubMed:11318637]
[WorldCat.org]
[DOI]
(P p)
