Difference between revisions of "MreBH"
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** close to the inner surface of the cytoplasmic membrane [http://www.ncbi.nlm.nih.gov/sites/entrez/16950129 PubMed] | ** close to the inner surface of the cytoplasmic membrane [http://www.ncbi.nlm.nih.gov/sites/entrez/16950129 PubMed] | ||
** reports on helical structures formed by MreBH {{PubMed|16950129,20566861}} seem to be misinterpretation of data {{PubMed|21636744}} | ** reports on helical structures formed by MreBH {{PubMed|16950129,20566861}} seem to be misinterpretation of data {{PubMed|21636744}} | ||
| + | ** normal localization depends on the presence of glucolipids, [[MreB]] forms irregular clusters in an ''[[ugtP]]'' mutant {{PubMed|22362028}} | ||
=== Database entries === | === Database entries === | ||
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* '''[[Sigma factor]]:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed] | * '''[[Sigma factor]]:''' [[SigI]] [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed] | ||
| − | * '''Regulation:''' induced by heat ([[SigI]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed] | + | * '''Regulation:''' |
| + | ** induced by heat ([[SigI]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed] | ||
| + | ** expression is increased in an ''[[ugtP]]'' mutant {{PubMed|22362028}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
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=References= | =References= | ||
==Localization== | ==Localization== | ||
| − | <pubmed> 17064365, 20566861 21636744,21636745 </pubmed> | + | <pubmed> 17064365, 20566861 21636744,21636745 22362028 </pubmed> |
==Other original publications== | ==Other original publications== | ||
<pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484</pubmed> | <pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 15:23, 4 March 2012
- Description: cell shape-determining protein, forms filaments, the polymers control/restrict the mobility of the cell wall elongation enzyme comple
| Gene name | mreBH |
| Synonyms | |
| Essential | no |
| Product | cell shape-determining protein |
| Function | cell shape determation |
| Interactions involving this protein in SubtInteract: MreBH | |
| MW, pI | 35 kDa, 5.239 |
| Gene length, protein length | 1005 bp, 335 aa |
| Immediate neighbours | ykpC, abh |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell shape, heat shock proteins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU14470
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- forms ring-shaped filaments in a heterologous system PubMed
- Protein family: ftsA/mreB family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- during logarithmic growth, MreBH forms discrete patches thst move processively along peripheral tracks perpendicular to the cell axis PubMed
- forms transverse bands as cells enter the stationary phase PubMed
- close to the inner surface of the cytoplasmic membrane PubMed
- reports on helical structures formed by MreBH PubMed seem to be misinterpretation of data PubMed
- normal localization depends on the presence of glucolipids, MreB forms irregular clusters in an ugtP mutant PubMed
Database entries
- Structure:
- UniProt: P39763
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
Localization
Other original publications
