Difference between revisions of "SpoVC"
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* '''Operon:''' | * '''Operon:''' | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pth_59504_60070_1 spoVC] {{PubMed|22383849}} |
+ | |||
+ | * '''Sigma factor:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
* '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed] | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 10:55, 12 April 2012
- Description: general stress protein, peptidyl-tRNA hydrolase
Gene name | spoVC |
Synonyms | pth |
Essential | yes PubMed |
Product | peptidyl-tRNA hydrolase |
Function | spore coat formation |
MW, pI | 20 kDa, 5.58 |
Gene length, protein length | 564 bp, 188 aa |
Immediate neighbours | ctc, fin |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
translation, general stress proteins (controlled by SigB), essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00530
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA (according to Swiss-Prot)
- Protein family: PTH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37470
- KEGG entry: [2]
- E.C. number: 3.1.1.29
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jeanne Menez, Richard H Buckingham, Miklos de Zamaroczy, Celine Karmazyn Campelli
Peptidyl-tRNA hydrolase in Bacillus subtilis, encoded by spoVC, is essential to vegetative growth, whereas the homologous enzyme in Saccharomyces cerevisiae is dispensable.
Mol Microbiol: 2002, 45(1);123-9
[PubMed:12100553]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)