Difference between revisions of "YsnA"
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Revision as of 14:38, 16 April 2012
- Description: ITPase
Gene name | ysnA |
Synonyms | |
Essential | no |
Product | ITPase |
Function | purine metabolism |
Metabolic function and regulation of this protein in SubtiPathways: Thiamin | |
MW, pI | 21 kDa, 4.95 |
Gene length, protein length | 594 bp, 198 aa |
Immediate neighbours | ysnB, rph |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28360
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: NTP + H2O = NDP + phosphate (according to Swiss-Prot)
- Protein family: HAM1 NTPase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P94558
- KEGG entry: [2]
- E.C. number: 3.6.1.15
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
S Lin, A G McLennan, K Ying, Z Wang, S Gu, H Jin, C Wu, W Liu, Y Yuan, R Tang, Y Xie, Y Mao
Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene.
J Biol Chem: 2001, 276(22);18695-701
[PubMed:11278832]
[WorldCat.org]
[DOI]
(P p)
K Y Hwang, J H Chung, S H Kim, Y S Han, Y Cho
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Nat Struct Biol: 1999, 6(7);691-6
[PubMed:10404228]
[WorldCat.org]
[DOI]
(P p)